What is the mechanism of Parkinson's disease?
Approved answer
Mechanisms Involved in Parkinson's Disease
The mechanisms recognized in the progression of Parkinson's disease (PD) encompass the aggregation of α-synuclein, oxidative stress, ferroptosis, mitochondrial impairments, neuroinflammation, and changes in gut microbiota. The interplay among these molecular factors adds complexity to the pathogenesis of PD and creates significant obstacles for drug development. Additionally, various signaling pathways are implicated in Parkinson's disease conditions.