What is the safest anesthesia for humans?

Local Anesthesia Versus General Anesthesia

Local anesthesia is generally considered safer than general anesthesia, as it avoids the systemic effects associated with the latter. Additionally, the side effects related to local anesthesia tend to be less severe, although it may still cause minor issues such as swelling and redness at the site of injection, or in rare cases, an allergic reaction.