What is the correct mechanism for Parkinson's disease?
Approved answer
Mechanisms of Parkinson's Disease
The known mechanisms associated with Parkinson's disease (PD) encompass α-synuclein aggregation, oxidative stress, ferroptosis, mitochondrial dysfunction, neuroinflammation, and gut dysbiosis. These interconnected molecular mechanisms add complexity to the pathogenesis of PD and present significant obstacles to effective drug development.