Side Effects of Folic Acid
Folic acid supplements are generally considered safe for most individuals. However, in very rare cases, they may lead to certain side effects that necessitate medical consultation. Below, we outline some of these potential side effects.
Allergic Reactions
In rare instances, folic acid may trigger a severe allergic reaction. If any of the following symptoms occur, immediate medical attention should be sought:
- Fever.
- General weakness and discomfort.
- Skin redness, itching, and rash.
- Tightness or difficulty in breathing.
- Difficulty swallowing.
- Wheezing.
Other Side Effects
There are a few additional side effects associated with folic acid that are exceedingly rare, with a prevalence rate below 0.1%. These may include:
- Gastrointestinal disturbances: such as nausea, bloating, and gas.
- Neurological issues: including a bitter taste in the mouth, changes in sleep patterns, difficulty concentrating, and hyperactivity.
- Psychological disorders: such as irritability, depression, and confusion.
- Other symptoms: including anorexia nervosa.
Specific Warnings Regarding Folic Acid Consumption
It is important to consider certain conditions before taking folic acid supplements, such as:
- Cancer: Individuals with a history of cancer should avoid high doses of folic acid. Research has indicated that daily intake of 800-1000 micrograms may elevate the risk of colorectal cancer.
- Heart Disease: Studies suggest that concurrent intake of folic acid and Vitamin B6 may increase the likelihood of heart attacks in individuals with a history of heart disease.
- Vitamin B12 Deficiency Anemia: Taking folic acid can mask symptoms of anemia caused by Vitamin B12 deficiency, potentially delaying appropriate treatment.
- Seizure Disorders: For patients with epilepsy on medications such as phenobarbital and primidone, folic acid supplements might worsen seizure frequency.
Video: Benefits and Risks of Folic Acid for Non-Pregnant Individuals
While folic acid is primarily recommended for pregnant women, its benefits extend to non-pregnant individuals as well: