Effects of Hormonal Treatment for Breast Cancer

Positive Effects

Hormone therapy may be an effective approach in cases where breast cancer cells exhibit sensitivity to hormones, possessing receptors such as estrogen and progesterone on their surfaces. This therapeutic method aids in reducing the size of cancerous tumors prior to surgical removal, while also playing a crucial role in preventing tumor recurrence post-surgery. Furthermore, it helps to mitigate the spread of cancerous growths to other breast tissues and inhibits the proliferation of tumors if they have metastasized to other areas of the body.

Negative Effects

The side effects associated with hormone therapy for breast cancer can be categorized as follows:

Side Effects

Hormone therapy for breast cancer may result in various side effects, including, but not limited to:

  • Hot flashes, commonly referred to as hot flashes.
  • Mood swings.
  • Night sweats.
  • Vaginal dryness.
  • Fatigue and exhaustion.
  • Vaginal discharge.
  • Muscle aches.
  • Joint stiffness and pain.
  • Decreased libido.

Health Complications

While rare, hormone therapy for breast cancer can lead to several serious health complications, such as:

  • Blood clots: These are rare but potentially serious complications associated with hormone therapy. The formation of blood clots can lead to deep vein thrombosis (DVT) and, if a clot travels to the lungs, may cause a pulmonary embolism. Patients should seek immediate medical attention if they experience shortness of breath, chest pain, or swelling, redness, and pain in one leg.
  • Stroke: There may be an increased risk of stroke associated with hormone therapy in rare cases. Patients should contact emergency services if they experience severe headaches, confusion, or difficulty speaking and walking.
  • Uterine cancer: The risk of developing uterine cancer may rise for women undergoing hormone therapy, especially for those who have had treatment after menopause. It’s important to consult a healthcare provider immediately if they experience any vaginal bleeding.
  • Other complications: Additional health complications may arise, including osteoporosis, cataracts, and depression.

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