Causes of Amniotic Fluid Depletion

Amniotic Fluid

Amniotic fluid, also known as amniotic fluid, is defined as a clear, yellowish liquid that forms within the first 12 days following conception inside the amniotic sac. This sac is comprised of two membranes: the amniotic membrane and the chorion. The amniotic fluid surrounds the fetus in the uterus and plays a crucial role in numerous essential functions necessary for the healthy development of the fetus. It allows the fetus to move within the womb, promoting proper bone growth, and contains vital nutrients, hormones, and antibodies. Additionally, it serves as a protective barrier against shocks and injuries, supports the appropriate development of the lungs, and helps maintain a stable temperature around the fetus. It’s important to point out that both an excess and a deficiency of amniotic fluid can lead to complications for the fetus. Initially, this fluid is composed solely of water from the mother’s body, but as the pregnancy progresses, it gradually transitions to being primarily composed of fetal urine, completely changing to fetal urine by around the 20th week of pregnancy.

Causes of Amniotic Fluid Depletion

Typically, the amniotic sac ruptures when a woman goes into labor. However, in certain cases, the sac may rupture or leak amniotic fluid, leading to a decrease in fluid levels before the onset of labor. This condition generally occurs before the 37th week of pregnancy and affects approximately 3% of pregnancies. Medical professionals refer to this phenomenon as premature rupture of membranes (PROM), which accounts for nearly one-third of preterm deliveries. It’s crucial to note that a reduction in amniotic fluid around the fetus can lead to various complications, including respiratory distress syndrome, fetal distress, umbilical cord prolapse, placental abruption, and even fetal demise. Below are some of the causes associated with early membrane rupture and subsequent amniotic fluid depletion:

  • Contractions that exert pressure on the amniotic sac, resulting in rupture.
  • Infections in the urinary tract or sexually transmitted infections.
  • Underlying medical conditions such as lung diseases or Ehlers-Danlos syndrome.
  • Exposure to harmful substances like tobacco, drugs, or alcohol.
  • Amniocentesis, a medical procedure that involves extracting amniotic fluid for testing by inserting a needle through the abdominal wall into the uterus, which can take time to heal.
  • Cervical cerclage, a surgical procedure where stitches are placed in the cervix to prevent premature delivery, usually performed in women whose cervix may dilate due to the pressure from the growing fetus.

Normal Volume of Amniotic Fluid

Estimating the volume of amniotic fluid is relatively straightforward during the first trimester when the fluid volume correlates with fetal weight. For instance, the average volume of amniotic fluid at the 12th week of pregnancy is approximately 60 milliliters. By the 16th week of pregnancy, during amniocentesis, the average volume increases to about 175 milliliters. However, significant variability in the volume of amniotic fluid occurs after the 20th week of pregnancy. Studies indicate that amniotic fluid volume steadily increases during the second trimester, peaking between 400 to 1200 milliliters during weeks 34 to 38. It’s noteworthy that after week 38, the amount of amniotic fluid begins to decrease at a rate of roughly 125 milliliters per week.

Symptoms of Amniotic Fluid Depletion

A decrease in amniotic fluid may occur suddenly or gradually due to slow leaks. It’s often challenging to determine whether these leaks involve urine, vaginal discharge, or amniotic fluid, particularly in the later stages of pregnancy. This is because the bladder fills more quickly than normal, potentially leading to urinary leakage. Additionally, vaginal discharge tends to increase significantly in the final stages of pregnancy to facilitate childbirth. It’s important to recognize that the properties of amniotic fluid differ from both urine and vaginal secretions, as urine typically has a distinct odor, vaginal secretions are usually white or yellow, while amniotic fluid possesses the following characteristics:

  • Amniotic fluid is typically clear and can be white, possibly containing some mucus or blood.
  • This fluid is odorless.
  • The volume of leaked amniotic fluid is generally sufficient to be noticeable.

Risks Associated with Amniotic Fluid Depletion

Leaks of amniotic fluid can result in certain risks and complications that may affect both the baby and the mother. The following outlines the risks associated with amniotic fluid depletion based on the stage of pregnancy:

  • During the first or second trimester: Potential complications resulting from leaking amniotic fluid during these months of pregnancy include:
    • Birth defects.
    • Miscarriage.
    • Preterm birth.
    • Stillbirth.
  • During the third trimester: If the leak occurs during the later stages of pregnancy, it can lead to complications such as:
    • Labor difficulties, such as pressure on the umbilical cord, resulting in reduced oxygen supply to the fetus.
    • An increased likelihood of requiring a cesarean delivery.
    • Delayed fetal growth.

Video on Symptoms of Amniotic Fluid Depletion

Watch this video to learn about the symptoms of amniotic fluid depletion:

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