Effects of Antipsychotics

Side Effects of Typical Antipsychotics

One of the most notable examples of typical antipsychotics is Haloperidol, a medication utilized in the treatment of schizophrenia and various other mental disorders. These medications are associated with several common side effects, which include:

  • Headaches.
  • Insomnia.
  • Depression.
  • Dry mouth.
  • Nausea and vomiting.
  • Erectile dysfunction.
  • Urinary retention.
  • Hypotension.
  • Muscle rigidity.
  • Shortness of breath.
  • Irritability and confusion.

Side Effects of Atypical Antipsychotics

Atypical antipsychotics are characterized by having fewer side effects compared to their typical counterparts, making them suitable for long-term use. Examples of this class of medications include Risperidone, Quetiapine, and Paliperidone. These drugs are prescribed for a range of conditions, such as bipolar disorder, anxiety, psychosis, and obsessive-compulsive disorder. The side effects associated with atypical antipsychotics may include:

  • Dry mouth.
  • Blurred vision.
  • Constipation.
  • Dizziness.
  • Weight gain.
  • General weakness.
  • Sleep disturbances.
  • Parkinsonism.
  • Akathisia (restlessness and difficulty sitting still).

Complications of Antipsychotics

The administration of antipsychotic medications necessitates a careful consideration of the positive effects in alleviating psychotic symptoms against the long-term complications these drugs might entail. In some cases, these complications can significantly impact a patient’s quality of life. Generally, the complications differ between first-generation (typical) and second-generation (atypical) antipsychotics, as outlined below:

  • Complications of Typical Antipsychotics: These medications are believed to potentially cause several movement disorders, including:
    • Extrapyramidal disorder.
    • Hyperkinesia.
    • Tardive dyskinesia.
    • Dystonia.
    • Bradykinesia.
  • Complications of Atypical Antipsychotics: These are thought to contribute to metabolic issues, such as the risk of developing type 2 diabetes and obesity.
  • Common Complications: Certain complications may occur with both first- and second-generation antipsychotics. These include orthostatic hypotension, cardiac arrhythmia, and the risk of sudden cardiac arrest.

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